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Abatacept

Drug Abatacept


Pronunciation: a-BAT-a-sept

Generic Name: Abatacept

Brand Name: Orencia

Abatacept is used for:

Learn the signs of RA and how to relieve the pain.


Treating moderate to severe rheumatoid arthritis in adults. It is also used to treat certain types of moderate to severe juvenile arthritis in children. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.


Abatacept is a selective co-stimulation modulator. It works by stopping the immune system from attacking healthy tissues in the body.


Do NOT use Do NOT use Abatacept if:


  • you are allergic to any ingredient in Abatacept

  • you are using anakinra or a tumor necrosis factor (TNF) blocker (eg, etanercept)

  • Contact your doctor or health care provider right away if any of these apply to you.


    Before using Before using Abatacept:


    Some medical conditions may interact with Abatacept. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have an infection (including an infection that will not go away), tuberculosis (TB) or a positive skin test for TB, or you have recently been in close contact with someone who has had TB

  • if you are at risk for developing an infection or have a history of infections that keep coming back

  • if you have a history of chronic obstructive pulmonary disease (COPD), diabetes, or hepatitis

  • if you are scheduled for surgery, you recently received a vaccine, you are scheduled for a vaccine, or your vaccines need to be brought up to date

  • Some MEDICINES MAY INTERACT with Abatacept. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Rituximab or TNF blockers (eg, etanercept) because the risk of serious infection may be increased

  • Anakinra because the risk of side effects may be increased

  • Live vaccinations because their effectiveness may be decreased by Abatacept

  • This may not be a complete list of all interactions that may occur. Ask your health care provider if Abatacept may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.



    How to use How to use Abatacept:


    Use Abatacept as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Abatacept. Talk to your pharmacist if you have questions about this information.

  • Abatacept is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Abatacept at home, a health care provider will teach you how to use it. Be sure you understand how to use Abatacept. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • If you miss a dose of Abatacept, contact your doctor right away. Your doctor will establish a new dosing schedule.

  • Ask your health care provider any questions you may have about how to use Abatacept.


    Important safety information Important safety information:


  • Abatacept may cause dizziness. This effect may be worse if you use it with alcohol or certain medicines. Use Abatacept with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Abatacept may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.

  • Tell your doctor or dentist that you take Abatacept before you receive any medical or dental care, emergency care, or surgery.

  • Do not receive a live vaccine (eg, measles, mumps) while you are using or within 3 months after stopping therapy with Abatacept. Talk with your doctor before you receive any vaccine.

  • You may need to have a TB skin test before you begin using Abatacept. Contact your doctor with any questions you may have about whether you should receive a TB skin test before using Abatacept.

  • Rarely, patients using Abatacept have developed cancer. It is not known if Abatacept may have contributed to the development of cancer. Contact your doctor with any questions or concerns.

  • Diabetes patients - Abatacept may cause the results of some tests for blood glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

  • Use Abatacept with caution in the ELDERLY; they may be more sensitive to its effects, especially the risk of infection or cancer.

  • Caution is advised when using Abatacept in CHILDREN; they may be more sensitive to its effects, including diarrhea, cough, fever, or stomach pain.

  • Abatacept should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Abatacept while you are pregnant. It is not known if Abatacept is found in breast milk. Do not breast-feed while using Abatacept.


  • Possible side effects Possible side effects of Abatacept:


    All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:


    Dizziness; headache; mild pain, swelling, or redness at the injection site; mild sore throat; nausea; stomach upset; stuffy nose.


    Seek medical attention right away if any of these SEVERE side effects occur:

    Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills, fever, or persistent sore throat; flu-like symptoms; increased cough; increased, decreased, or painful urination; night sweats; severe or persistent dizziness; shortness of breath; unexplained weight loss; unusual lumps or growths; unusual tiredness; wheezing.


    This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


    If Overdose is suspected If Overdose is suspected:


    Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


    Proper storage of Abatacept:

    Abatacept is usually handled and stored by a health care provider. If you are using Abatacept at home, store Abatacept as directed by your pharmacist or health care provider. Keep Abatacept out of the reach of children and away from pets.


    General information General information:


  • If you have any questions about Abatacept, please talk with your doctor, pharmacist, or other health care provider.

  • Abatacept is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

  • This information is a summary only. It does not contain all information about Abatacept. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.




    Drugs: Abatacept

    Category: A

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