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Drug Levatol

Pronunciation: pen-BYOO-toe-lole

Generic Name: Penbutolol

Brand Name: Levatol

If you have angina or have had heart problems, DO NOT suddenly stop taking Levatol without first consulting with your doctor. Severe chest pain, heart attack, very fast heart rate, and irregular heart rhythm may occur. If your doctor decides you should no longer take Levatol, the dosage should be gradually reduced according to your doctor's instructions. You should be closely watched by your doctor and limit physical activity to a minimum, particularly if you have certain kinds of heart disease. Some medicines or medical conditions may interact with Levatol.

Levatol is used for:

Treating mild to moderate high blood pressure. It may be used along or with other medicines. It may also be used for other conditions as determined by your doctor.

Levatol is a beta-adrenergic blocking agent. It works by slowing down the heart and reducing blood pressure, which helps it pump more efficiently and reduces the workload on the heart. It may also interfere with the action of adrenalin and other similar chemicals in the brain.

Do NOT use Do NOT use Levatol if:

  • you are allergic to any ingredient in Levatol

  • you have a very slow heartbeat, heart block, uncontrolled heart failure, or shock caused by heart failure, or you have had a heart attack and have very low blood pressure

  • you have asthma or Raynaud phenomenon

  • you are a child with diabetes or heart failure

  • you are currently taking mibefradil

  • Contact your doctor or health care provider right away if any of these apply to you.

    Before using Before using Levatol:

    Some medical conditions may interact with Levatol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine (eg, medicines to treat colds or congestion), herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances or are taking medicine for allergies

  • if you have or have ever had an adrenal gland tumor; anaphylaxis; asthma, chronic bronchitis, chronic obstructive pulmonary disease [COPD], emphysema, or other lung disease; congestive heart failure; blood vessel problems; a slow heartbeat; diabetes; kidney problems; low blood sugar; or an overactive thyroid

  • if you have Wolff-Parkinson-White syndrome

  • if you are having surgery

  • Some MEDICINES MAY INTERACT with Levatol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antiarrhythmics (eg, amiodarone, flecainide, quinidine), antipsychotics (eg, chlorpromazine, haloperidol), bupivacaine, calcium channel blockers (eg, mibefradil, nifedipine, verapamil), catecholamine-depleting agents (eg, reserpine), cimetidine, ketanserin, mefloquine, or thioamines (eg, tapazole) because potentially life-threatening heart-related side effects may occur, including very slow heart rate; abnormal heartbeat; lightheadedness, especially upon standing; difficulty breathing, especially when lying down; loss of function in the heart and lungs; and swelling of ankles

  • Barbiturates (eg, phenobarbital), clonidine, phenytoin, rifampin, or thyroid hormones (eg, levothyroxine) because the effectiveness of Levatol may be decreased

  • Certain stimulants (adrenalin, pseudoephedrine), hydralazine, insulin, lidocaine, quinazolines (eg, doxazosin), rizatriptan, or theophylline because actions and side effects may be increased by Levatol

  • This may not be a complete list of all interactions that may occur. Ask your health care provider if Levatol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    How to use How to use Levatol:

    Use Levatol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Levatol may be taken with or without food.

  • Do not take antacids containing aluminum within 2 hours of Levatol.

  • Take Levatol at the same time each day.

  • Continue to use Levatol even if you feel well. Do not miss any doses.

  • If you miss a dose of Levatol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

  • Ask your health care provider any questions you may have about how to use Levatol.

    Important safety information Important safety information:

  • Levatol may cause drowsiness, dizziness, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Levatol. Using Levatol alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.

  • Levatol may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.

  • Do not suddenly stop taking Levatol without first checking with your doctor.

  • Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medication even though you may not feel quite "normal." Contact your doctor or pharmacist about any new symptoms.

  • Levatol may mask the signs of hyperthyroidism (overactive thyroid). If thyroid patients stop taking these medicines too suddenly, symptoms of hyperthyroidism (eg, a rapid pulse) may occur.

  • Patients with a history of severe allergic reactions may be more sensitive to allergens while taking Levatol. These patients may not respond to the usual dose of epinephrine (adrenalin).

  • Levatol may interfere with the glaucoma screening test.

  • Diabetes patients - Levatol may mask signs of low blood sugar such as a rapid heartbeat. Other symptoms, such as sweating, may still occur. Levatol may affect blood sugar levels. Your doctor may need to change the dose of diabetes medicine you take. Check blood glucose levels regularly.

  • Before having any surgical or dental procedures or receiving emergency treatment, tell the doctor or dentist in charge that you are receiving Levatol.

  • LAB TESTS may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Levatol with caution in the ELDERLY because they may be more sensitive to its effects, especially slow heartbeat.

  • Use Levatol with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Levatol during pregnancy. It is unknown if Levatol is excreted in breast milk. If you are or will be breast-feeding while you are using Levatol, check with your doctor or pharmacist to discuss the risks to your baby.

  • If you suddenly stop taking Levatol, you may experience WITHDRAWAL symptoms, including worsening chest pain along with possible heart attack.

    Possible side effects Possible side effects of Levatol:

    All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

    Constipation; depression; diarrhea; dizziness; drowsiness; fatigue; hallucinations; lightheadedness; nausea; sleeplessness; stomach cramps; tiredness; vision problems; vivid dreams; vomiting; weakness.

    Seek medical attention right away if any of these SEVERE side effects occur:

    Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); shortness of breath; slow or irregular heartbeat.

    This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

    If Overdose is suspected If Overdose is suspected:

    Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing, especially when lying down; lightheadedness, especially upon standing; pale or blue skin; seizures (convulsions); shortness of breath; swelling of ankles; unconsciousness, possibly leading to lack of heartbeat or breathing; very slow heart rate; wheezing.

    Proper storage of Levatol:

    Store Levatol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Levatol out of the reach of children and away from pets.

    General information General information:

  • If you have any questions about Levatol, please talk with your doctor, pharmacist, or other health care provider.

  • Levatol is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

  • This information is a summary only. It does not contain all information about Levatol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

    Drugs: Levatol

    Category: L

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